Anti-Filamin A antibody [EP2405Y],Abcam,AB76289
What is this antibody validated in? Anti-Filamin A antibody [EP2405Y] (ab76289) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in African green monkey, Human, Mouse, Rat samples. What is the molecular weight of Filamin A? Anti-Filamin A [EP2405Y] (ab76289) specifically detects a band for Filamin A (UniProt: P21333) at a molecular weight of 281kDa. Trusted by the scientific community Anti-Filamin A [EP2405Y] (ab76289) was first used in a scientific publication in 2009 and has been cited over 40 times in peer-reviewed journals. Reviewed by scientists Anti-Filamin A [EP2405Y] (ab76289) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Filamin A antibody [EP2405Y] (ab76289) has been confirmed by Western blot testing in FLNA Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EP2405Y] also available for your convenience: ab76289, Carrier free - ab239881 , Alexa Fluor ® 488 - ab246749 , Alexa Fluor ® 647 - ab246750 , PE - ab246751 , APC - ab310878 , Alexa Fluor ® 594 - ab311706 , Alexa Fluor ® 568 - ab312981 , Alexa Fluor ® 555 - ab313188 , Alexa Fluor ® 750 - ab321721 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human, African green monkey
Application
WB, IHC-P, Flow Cyt (Intra), ICC/IF
Platform ID
BAB178935892
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity). During the axon guidance process, required for growth cone collapse induced by SEMA3A-mediated stimulation of neurons (PubMed : 25358863). See full target information FLNA
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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