Anti-Filamin C antibody,Abcam,AB244284

Host

Rabbit

Reactivity

Human

Application

IHC-P, ICC/IF

Platform ID

BAB179035844

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Filamin C antibody
Cat. No.AB244284
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, ICC/IF
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human FLNC aa 2600 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Muscle-specific filamin, which plays a central role in sarcomere assembly and organization (PubMed : 34405687). Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events (By similarity). See full target information FLNC

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