Anti-Folate Receptor 4 antibody,Abcam,AB233142

Host

Rabbit

Reactivity

Mouse

Application

WB, IHC-P

Platform ID

BAB058970974

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Folate Receptor 4 antibody
Cat. No.AB233142
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationWB, IHC-P
ClonalityPolyclonal
Concentration0.5 - 1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Mouse Izumo1r aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization (PubMed : 24739963, PubMed : 26859261, PubMed : 27309808, PubMed : 27416963). The IZUMO1 : IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed : 24739963, PubMed : 26859261, PubMed : 27309808). The ligand-receptor interaction probably does not act as a membrane 'fusogen' (PubMed : 24739963, PubMed : 26859261, PubMed : 27309808). Does not bind folate (PubMed : 24739963). See full target information Izumo1r

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.