Anti-GABARAP+GABARAPL1+GABARAPL2 antibody [EPR4805],Abcam,AB109364
What is this antibody validated in? Anti-GABARAP+GABARAPL1+GABARAPL2 antibody [EPR4805] (ab109364) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of GABARAP+GABARAPL1+GABARAPL2? Anti-GABARAP+GABARAPL1+GABARAPL2 [EPR4805] (ab109364) specifically detects a band for GABARAP+GABARAPL1+GABARAPL2 (UniProt: O95166) at a molecular weight of 14kDa. Trusted by the scientific community Anti-GABARAP+GABARAPL1+GABARAPL2 [EPR4805] (ab109364) was first used in a scientific publication in 2011 and has been cited over 60 times in peer-reviewed journals. Reviewed by scientists Anti-GABARAP+GABARAPL1+GABARAPL2 [EPR4805] (ab109364) has over 10 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR4805] also available for your convenience: ab109364, HRP - ab201813 , Carrier free - ab225535 , Alexa Fluor® 488 - ab319582 , Alexa Fluor® 647 - ab319688 , Alexa Fluor® 594 - ab319818 , Alexa Fluor® 555 - ab319959 , Alexa Fluor® 750 - ab320947 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
Flow Cyt (Intra), ICC/IF, WB, IHC-P
Platform ID
BAB500038011
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton (PubMed : 9892355). Involved in autophagy : while LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed : 15169837, PubMed : 20562859, PubMed : 22948227). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed : 31006538). Also required for the local activation of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex, regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) that activates RAC1 and downstream signal transduction (PubMed : 25684205). Thereby, regulates different biological processes including the organization of the cytoskeleton, cell migration and proliferation (PubMed : 25684205). Involved in apoptosis (PubMed : 15977068). See full target information GABARAP Additional targets GABARAPL1,GABARAPL2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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