Anti-GAD67/GAD1 antibody [K-87],Abcam,AB26116

ab26116 mouse monoclonal [K-87] to GAD67 specically recognizes GAD67 and has no cross reactivity with GAD65; this has been shown on western blots of mouse brain or purified recombinant GAD67 and GAD65. In immunohistochemical analysis of brain sections, the K-87 monoclonal recognizes GAD67 in nerve cell bodies and has an enhanced ability to detect GAD67 in dendrites and axon buttons compared to the original anti-GAD67 K-2 polyclonal antibody (see Kaufman et al, 1991). Product Specifications Mouse monoclonal [K-87] to GAD67/GAD1 (ab26116) is a mouse monoclonal antibody and is validated for use in Flow Cyt, ICC/IF, IHC-P, WB in human, mouse, rat samples. Mouse monoclonal [K-87] to GAD67/GAD1 (ab26116) specifically detects GAD67/GAD1 (UniProt ID: Q99259; Molecular weight: 67kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Mouse monoclonal [K-87] to GAD67/GAD1 (ab26116) has high sensitivity and specificity. Mouse monoclonal [K-87] to GAD67/GAD1 (ab26116) has been cited over 104 times in peer reviewed journals and is trusted by the scientific community. Mouse monoclonal [K-87] to GAD67/GAD1 (ab26116) has 19 independent reviews from customers.

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

IHC-P, WB, ICC/IF, Flow Cyt

Platform ID

BAB750362855

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GAD67/GAD1 antibody [K-87]
Cat. No.AB26116
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Human
ApplicationIHC-P, WB, ICC/IF, Flow Cyt
ClonalityMonoclonal
Clone NumberK-87
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human GAD1 aa 50-150. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.01% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.. Isoform 3. Enzymatically inactive as glutamate decarboxylase. See full target information GAD1

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