Anti-GATA1 antibody,Abcam,AB11852

What is this antibody validated in? Anti-GATA1 antibody (ab11852) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human samples. What is the molecular weight of GATA1? Anti-GATA1 (ab11852) specifically detects a band for GATA1 (UniProt: P15976) at a molecular weight of 43kDa. Trusted by the scientific community Anti-GATA1 (ab11852) was first used in a scientific publication in 2004 and has been cited over 20 times in peer-reviewed journals.

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB439955600

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GATA1 antibody
Cat. No.AB11852
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration1.3 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human GATA1 aa 350 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional activator or repressor which serves as a general switch factor for erythroid development (PubMed : 35030251). It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed : 24245781). See full target information GATA1

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