Anti-GATA1 antibody - N-terminal,Abcam,AB173816

Host

Rabbit

Reactivity

Human

Application

ICC/IF, IHC-P, WB

Platform ID

BAB565018070

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GATA1 antibody - N-terminal
Cat. No.AB173816
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, IHC-P, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human GATA1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional activator or repressor which serves as a general switch factor for erythroid development (PubMed : 35030251). It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed : 24245781). See full target information GATA1

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