Anti-GATA3 antibody [EPR16651] - ChIP Grade,Abcam,AB199428
Anti-GATA3 antibody [EPR16651] - ChIP Grade (ab199428) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ChIP, Flow Cyt (Intra), ICC/IF, IHC-P, WB in human, mouse samples. Anti-GATA3 antibody [EPR16651] - ChIP Grade (ab199428) has been cited over 65 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-GATA3 antibody [EPR16651] - ChIP Grade (ab199428) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-GATA3 antibody [EPR16651] - ChIP Grade (ab199428) has been confirmed by testing in knockout samples. Anti-GATA3 antibody [EPR16651] - ChIP Grade (ab199428) has 12 independent reviews from customers. Anti-GATA3 antibody [EPR16651] - ChIP Grade (ab199428) specifically detects GATA3 (UniProt ID: P23771; Molecular weight: 48kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR16651 - ab21484 . Antibody clone EPR16651 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 555, PE ( ab28895 , ab28896 , ab21672 , ab225419 ). GATA3 is crucial for T-cell development and differentiation, and its dysregulation is linked to diseases like breast cancer, T-cell lymphomas, and autoimmune disorders. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Human, Mouse
Application
Flow Cyt (Intra), ChIP, WB, ICC/IF, IHC-P
Platform ID
BAB940105528
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages. See full target information GATA3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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