Anti-GC-C antibody [2E5] - Human IgG1 (Chimeric),Abcam,AB314020
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Mouse
Reactivity
Human
Application
FuncS, Flow Cyt
Platform ID
BAB815642770
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-GC-C antibody [2E5] - Human IgG1 (Chimeric)
Cat. No.AB314020
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFuncS, Flow Cyt
ClonalityMonoclonal
Clone Number2E5
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human GUCY2C.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP (PubMed : 11950846, PubMed : 1718270, PubMed : 22436048, PubMed : 22521417, PubMed : 23269669). Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed : 1680854, PubMed : 1718270). Also activated by the endogenous peptides guanylin and uroguanylin (PubMed : 8381596). See full target information GUCY2C
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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