Anti-GC-C antibody,Abcam,AB122404
Host
Rabbit
Reactivity
Human
Application
IHC-P
Platform ID
BAB128149017
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-GC-C antibody
Cat. No.AB122404
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.15 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human GUCY2C aa 950 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP (PubMed : 11950846, PubMed : 1718270, PubMed : 22436048, PubMed : 22521417, PubMed : 23269669). Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed : 1680854, PubMed : 1718270). Also activated by the endogenous peptides guanylin and uroguanylin (PubMed : 8381596). See full target information GUCY2C
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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