Anti-GDNF antibody [BS376],Abcam,AB244211
Host
Mouse
Reactivity
Rat, Human
Application
Flow Cyt (Intra), ICC/IF
Platform ID
BAB941604808
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-GDNF antibody [BS376]
Cat. No.AB244211
HostMouse
IsotypeIgG3
ReactivityRat, Human
ApplicationFlow Cyt (Intra), ICC/IF
ClonalityMonoclonal
Clone NumberBS376
ImmunogenSynthetic Peptide within Human GDNF aa 50-100. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLyophilized
ShippingBlue Ice
FormulationpH: 7 - 7.4 Constituents: PBS, 3% Trehalose
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake (PubMed : 8493557). Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor (PubMed : 10829012, PubMed : 25242331, PubMed : 31535977). Involved in the development of the neural crest (PubMed : 15242795). See full target information GDNF
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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