Anti-GFAP antibody - Astrocyte Marker,Abcam,AB7260

Find all reagents to label astrocytes in our " Astrocytes markers guide ". Anti-GFAP antibody (ab7260) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC (PFA fixed), IHC-P, IP and WB. Anti-GFAP antibody (ab7260) was first used in a scientific publication in 2006 and has been cited over 1203 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-GFAP antibody (ab7260) has high sensitivity and specificity. Anti-GFAP antibody (ab7260) has 103 independent reviews from customers. Anti-GFAP antibody (ab7260) specifically detects GFAP (UniProt ID: P14136; Molecular weight: 50kDa) and is sold in 50 µL selling sizes. GFAP (Glial Fibrillary Acidic Protein) is a key marker in neuro research, particularly for its role in identifying astrocyte activity. It is predominantly expressed in astrocytes, the most abundant glial cells in the brain and spinal cord. Altered GFAP levels are associated with various neurological conditions, including Alzheimer's disease (AD), traumatic brain injury (TBI) and multiple sclerosis (MS). Researchers use GFAP to assess astrocytic response and neuroinflammation, making it essential for understanding the extent of brain injury and the progression of neurodegenerative diseases.

Host

Rabbit

Reactivity

Mouse, Rat

Application

IHC-P, IHC (PFA fixed), IP, ICC/IF, WB

Platform ID

BAB004585827

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GFAP antibody - Astrocyte Marker
Cat. No.AB7260
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationIHC-P, IHC (PFA fixed), IP, ICC/IF, WB
ClonalityPolyclonal
ImmunogenRecombinant Full Length Protein corresponding to Human GFAP.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.03% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. See full target information GFAP

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