Anti-GFAP antibody - Astrocyte Marker,Abcam,AB53554

Find all reagents to label astrocytes in our " Astrocytes markers guide ". Anti-GFAP antibody (ab53554) is a Goat Polyclonal antibody and is validated for use in WB in cow, human, mouse, rat samples. Anti-GFAP antibody (ab53554) has been cited over 392 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-GFAP antibody (ab53554) has high sensitivity and specificity. Anti-GFAP antibody (ab53554) has 24 independent reviews from customers. Anti-GFAP antibody (ab53554) specifically detects GFAP (UniProt ID: P14136; Molecular weight: 50kDa) and is sold in 100 ug selling sizes. GFAP (Glial Fibrillary Acidic Protein) is a key marker in neuro research, particularly for its role in identifying astrocyte activity. It is predominantly expressed in astrocytes, the most abundant glial cells in the brain and spinal cord. Altered GFAP levels are associated with various neurological conditions, including Alzheimer's disease (AD), traumatic brain injury (TBI), and multiple sclerosis (MS). Researchers use GFAP to assess astrocytic response and neuroinflammation, making it essential for understanding the extent of brain injury and the progression of neurodegenerative diseases.

Host

Goat

Reactivity

Mouse, Rat, Human

Application

WB

Platform ID

BAB692079580

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GFAP antibody - Astrocyte Marker
Cat. No.AB53554
HostGoat
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human GFAP aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 0.5% BSA, 0.5% Tris
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. See full target information GFAP

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