Anti-GFAP antibody [EPR1034Y] - Astrocyte Marker,Abcam,AB68428

Find all reagents to label astrocytes in our " Astrocytes markers guide ". Anti-GFAP antibody [EPR1034Y] (ab68428) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, IP and WB. Anti-GFAP antibody [EPR1034Y] (ab68428) was first used in a scientific publication in 2011 and has been cited over 106 times in peer reviewed journals. It's performance in IHC in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-GFAP antibody [EPR1034Y] (ab68428) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-GFAP antibody [EPR1034Y] (ab68428) has 15 independent reviews from customers. Anti-GFAP antibody [EPR1034Y] (ab68428) specifically detects GFAP (UniProt ID: P14136; Molecular weight: 50kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR1034Y - ab218309 . Antibody clone EPR1034Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 555, Alexa Fluor ® 568, Alexa Fluor ® 405, PE, APC, HRP, Alkaline Phosphatase, Alexa Fluor ® 647, Biotin, Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 647, Alexa Fluor ® 488, Alexa Fluor ® 488 ( ab194324 , ab194325 , ab201732 , ab201735 , ab201736 , ab206586 , ab303005 , ab303006 , ab303007 , ab308965 , ab313596 , ab314264 , ab317669 , ab317720 , ab317721 , ab317762 , ab319022 ). NEW: Explore our alternative host species for clone [EPR1034Y] : goat, chicken, rat, mouse. GFAP (Glial Fibrillary Acidic Protein) is a key marker in neuro research, particularly for its role in identifying astrocyte activity. It is predominantly expressed in astrocytes, the most abundant glial cells in the brain and spinal cord. Altered GFAP levels are associated with various neurological conditions, including Alzheimer's disease (AD), traumatic brain injury (TBI) and multiple sclerosis (MS). Researchers use GFAP to assess astrocytic response and neuroinflammation, making it essential for understanding the extent of brain injury and the progression of neurodegenerative diseases. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-Fr, IHC-P, ICC/IF, mIHC, Flow Cyt (Intra), IP, WB

Platform ID

BAB254610815

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GFAP antibody [EPR1034Y] - Astrocyte Marker
Cat. No.AB68428
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-Fr, IHC-P, ICC/IF, mIHC, Flow Cyt (Intra), IP, WB
ClonalityMonoclonal
Clone NumberEPR1034Y
Concentration0.052 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.21% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. See full target information GFAP

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