Anti-GFM2 antibody,Abcam,AB229463

Host

Rabbit

Reactivity

Mouse, Human

Application

ICC/IF, IHC-P, WB

Platform ID

BAB942304472

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-GFM2 antibody
Cat. No.AB229463
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, IHC-P, WB
ClonalityPolyclonal
Concentration0.62 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human GFM2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis (PubMed : 19716793, PubMed : 33878294). Acts in collaboration with MRRF (PubMed : 19716793, PubMed : 33878294). Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts (PubMed : 33878294). GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit (PubMed : 19716793). Not involved in the GTP-dependent ribosomal translocation step during translation elongation (PubMed : 19716793). See full target information GFM2

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