Anti-GPAM antibody,Abcam,AB68925

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB071964734

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GPAM antibody
Cat. No.AB68925
HostMouse
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human GPAM.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids (PubMed : 18238778, PubMed : 19075029, PubMed : 36522428). Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid (PubMed : 18238778). Has a narrow hydrophobic binding cleft that selects for a linear acyl chain (PubMed : 36522428). Catalytic activity is higher for substrates with a 16-carbon acyl chain (PubMed : 36522428). See full target information GPAM

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