Anti-GPAM antibody,Abcam,AB69990

Host

Rabbit

Reactivity

Rat

Application

WB

Platform ID

BAB384470981

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GPAM antibody
Cat. No.AB69990
HostRabbit
IsotypeIgG
ReactivityRat
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human GPAM. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids (PubMed : 18238778, PubMed : 19075029, PubMed : 36522428). Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid (PubMed : 18238778). Has a narrow hydrophobic binding cleft that selects for a linear acyl chain (PubMed : 36522428). Catalytic activity is higher for substrates with a 16-carbon acyl chain (PubMed : 36522428). See full target information GPAM

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