Anti-GRIM19 antibody [6E1BH7],Abcam,AB110240

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat, Cow, Human

Application

ICC/IF, Flow Cyt, WB

Platform ID

BAB886619949

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-GRIM19 antibody [6E1BH7]
Cat. No.AB110240
HostMouse
IsotypeIgG2b
ReactivityMouse, Rat, Cow, Human
ApplicationICC/IF, Flow Cyt, WB
ClonalityMonoclonal
Clone Number6E1BH7
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: HEPES buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed : 27626371). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed : 27626371). Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed : 15753091). See full target information NDUFA13

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