Anti-GRK1 antibody [D11],Abcam,AB2776

Host

Mouse

Reactivity

Mouse, Cow, Human

Application

ICC/IF

Platform ID

BAB636694913

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GRK1 antibody [D11]
Cat. No.AB2776
HostMouse
IsotypeIgG
ReactivityMouse, Cow, Human
ApplicationICC/IF
ClonalityMonoclonal
Clone NumberD11
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human GRK1.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade (PubMed : 15946941). This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (By similarity). May play a role in the maintenance of the outer nuclear layer in the retina (By similarity). See full target information GRK1

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