Anti-GRP94 antibody [EPR22847-50],Abcam,AB238126

What is this antibody validated in? Anti-GRP94 antibody [EPR22847-50] (ab238126) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of GRP94? Anti-GRP94 [EPR22847-50] (ab238126) specifically detects a band for GRP94 (UniProt: P14625) at a molecular weight of 94kDa. Trusted by the scientific community Anti-GRP94 [EPR22847-50] (ab238126) was first used in a scientific publication in 2019 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-GRP94 antibody [EPR22847-50] (ab238126) has been confirmed by Western blot testing in HSP90B1 Knockout HEK293T cell line, ab266313 . Other related products We have a range of other formats of antibody clone [EPR22847-50] also available for your convenience: ab238126, Carrier free - ab256312 , Alexa Fluor® 647 - ab313672 , Alexa Fluor® 488 - ab314591 , APC - ab317477 , PE - ab322454 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Flow Cyt (Intra), IHC-P, IP, ICC/IF, WB

Platform ID

BAB074763390

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-GRP94 antibody [EPR22847-50]
Cat. No.AB238126
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationFlow Cyt (Intra), IHC-P, IP, ICC/IF, WB
ClonalityMonoclonal
Clone NumberEPR22847-50
Concentration0.615 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed : 18264092). Has ATPase activity (By similarity). May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed : 32272059). See full target information HSP90B1

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