Anti-Galectin 1 + Galectin 3 + Galectin 8 antibody [RM1261],Abcam,AB322347

What are recombinant multiclonals? Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including: - The sensitivity of polyclonal antibodies by recognising multiple epitopes - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production View our range of recombinant multiclonal antibodies . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, ICC/IF, IHC-P, Flow Cyt (Intra)

Platform ID

BAB375775157

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Galectin 1 + Galectin 3 + Galectin 8 antibody [RM1261]
Cat. No.AB322347
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, ICC/IF, IHC-P, Flow Cyt (Intra)
ClonalityMulticlonal
Clone NumberRM1261
Concentration0.51 mg/mL Batch dependent concentration
ImmunogenThis product was produced with the following immunogens:
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69 (PubMed : 24752896). See full target information LGALS1 Additional targets LGALS3,LGALS8,Lgals3,Lgals8,Lgals1,Lgals3,Lgals8,Lgals1

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