Anti-Galectin 1 antibody,Abcam,AB154351

Host

Rabbit

Reactivity

Mouse, Human

Application

IP, ICC/IF, WB

Platform ID

BAB688181452

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Galectin 1 antibody
Cat. No.AB154351
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIP, ICC/IF, WB
ClonalityPolyclonal
Concentration1.48 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human LGALS1 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69 (PubMed : 24752896). See full target information LGALS1

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