Anti-Galectin 1 antibody [SP247] - C-terminal,Abcam,AB192842

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, IHC-Fr, ICC/IF, IHC-P, Flow Cyt (Intra)

Platform ID

BAB063268910

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Galectin 1 antibody [SP247] - C-terminal
Cat. No.AB192842
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, IHC-Fr, ICC/IF, IHC-P, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberSP247
Concentration0.042 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69 (PubMed : 24752896). See full target information LGALS1

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