Anti-Galectin 3 antibody [EP2775Y],Abcam,AB76245

What is this antibody validated in? Anti-Galectin 3 antibody [EP2775Y] (ab76245) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Galectin 3? Anti-Galectin 3 [EP2775Y] (ab76245) specifically detects a band for Galectin 3 (UniProt: P17931) at a molecular weight of 26kDa. Trusted by the scientific community Anti-Galectin 3 [EP2775Y] (ab76245) was first used in a scientific publication in 2009 and has been cited over 30 times in peer-reviewed journals. Reviewed by scientists Anti-Galectin 3 [EP2775Y] (ab76245) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Galectin 3 antibody [EP2775Y] (ab76245) has been confirmed by Western blot testing in LGALS3 Knockout A549 cell line. Other related products We have a range of other formats of antibody clone [EP2775Y] also available for your convenience: ab76245, Carrier free - ab197544 , HRP - ab202553 , Alexa Fluor® 555 - ab279330 , Alexa Fluor® 488 - ab309974 , APC - ab310877 , PE - ab310938 , Alexa Fluor® 647 - ab311095 , Alexa Fluor® 594 - ab311705 , Alexa Fluor® 568 - ab312980 , Alexa Fluor® 750 - ab321720 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, Flow Cyt (Intra), ICC/IF, IHC-P

Platform ID

BAB438356368

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Galectin 3 antibody [EP2775Y]
Cat. No.AB76245
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, Flow Cyt (Intra), ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberEP2775Y
Concentration0.515 - 0.55 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus : acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. See full target information LGALS3

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