Anti-Gelsolin antibody,Abcam,AB214342

Contains a FLAG tag (DDDDK) and a His tag Therefore, an anti DDDDK or anti His secondary can be used. We recommend the anti-FLAG option ( ab49763 ). Please note: ab214342 only recognises the Ca2+ activated form of Human Gelsolin.

Host

Alpaca

Reactivity

Human

Application

IP, WB

Platform ID

BAB254211007

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Gelsolin antibody
Cat. No.AB214342
HostAlpaca
IsotypeVHH
ReactivityHuman
ApplicationIP, WB
ClonalityMonoclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification His Tag
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 2.9% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed : 19666512). Plays a role in ciliogenesis (PubMed : 20393563). See full target information GSN

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