Anti-Gelsolin antibody - C-terminal,Abcam,AB191134

Host

Rabbit

Reactivity

Mouse, Rat, Human, African green monkey

Application

WB, IHC-P, ICC

Platform ID

BAB566717254

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Gelsolin antibody - C-terminal
Cat. No.AB191134
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human, African green monkey
ApplicationWB, IHC-P, ICC
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human GSN aa 750 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate) Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Disodium hydrogenorthophosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed : 19666512). Plays a role in ciliogenesis (PubMed : 20393563). See full target information GSN

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