Anti-Gelsolin antibody [GS-2C4],Abcam,AB11081

This product was changed from ascites to tissue culture supernatant on 17 May 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Host

Mouse

Reactivity

Human

Application

WB, IP, ICC/IF

Platform ID

BAB754260983

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Gelsolin antibody [GS-2C4]
Cat. No.AB11081
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, IP, ICC/IF
ClonalityMonoclonal
Clone NumberGS-2C4
ImmunogenNative Full Length Protein corresponding to Human GSN.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.097% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed : 19666512). Plays a role in ciliogenesis (PubMed : 20393563). See full target information GSN

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