Anti-Gephyrin antibody,Abcam,AB228674

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, IHC-Fr, IP, ICC/IF, WB

Platform ID

BAB441954640

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Gephyrin antibody
Cat. No.AB228674
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, IHC-Fr, IP, ICC/IF, WB
ClonalityPolyclonal
Concentration0.59 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human GPHN. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors (PubMed : 25025157, PubMed : 26613940).. Has also a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. See full target information GPHN

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