Anti-Gli1 antibody [HL247] - BSA and Azide free,Abcam,AB289368
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Host
Rabbit
Reactivity
Mouse, Human, Rat
Application
ICC/IF, IHC-P, WB
Platform ID
BAB505935179

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Acts as a transcriptional activator (PubMed : 10806483, PubMed : 19706761, PubMed : 19878745, PubMed : 24076122, PubMed : 24217340, PubMed : 24311597). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed : 2105456, PubMed : 24217340, PubMed : 8378770). Regulates the transcription of specific genes during normal development (PubMed : 19706761). Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed : 19706761, PubMed : 28973407). Plays a role in cell proliferation and differentiation via its role in SHH signaling (PubMed : 11238441, PubMed : 28973407).. Isoform 2. Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH signaling. Promotes cancer cell migration. See full target information GLI1
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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