Anti-Glucose Transporter GLUT1 antibody [EPR3915],Abcam,AB115730

Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730) was first used in a scientific publication in 2012 and has been cited over 320 times in peer reviewed journals. It's performance in Western Blot in human and mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730) has been confirmed by Western Blot testing in Glucose Transporter GLUT1 knockout HepG2 cells ( ab280797 ). Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730) has 18 independent reviews from customers. Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730) specifically detects Glucose Transporter GLUT1 (UniProt ID: P11166; Molecular weight: 55kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR3915 - ab196357 . Antibody clone EPR3915 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647, HRP, Alexa Fluor ® 488, Alexa Fluor ® 594, PE, Alexa Fluor ® 405, APC, FITC ( ab195020 , ab195021 , ab195359 , ab206360 , ab209449 , ab210438 , ab316298 , ab322306 ). GLUT1 significantly impacts inflammation by facilitating glucose uptake in immune cells, which is essential for their activation and function. GLUT1 activity can lead to chronic inflammation and tissue damage. GLUT1 is a key biomarker in IBD and immunometabolism. GLUT1 is a signature in Met-flow analysis. Antibody is top cited with over 428 publications. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Flow Cyt (Intra), ICC/IF, WB, IHC-P

Platform ID

BAB381772277

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Glucose Transporter GLUT1 antibody [EPR3915]
Cat. No.AB115730
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationFlow Cyt (Intra), ICC/IF, WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR3915
Concentration0.179 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed : 10227690, PubMed : 10954735, PubMed : 18245775, PubMed : 19449892, PubMed : 25982116, PubMed : 27078104, PubMed : 32860739). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed : 18245775, PubMed : 19449892). Most important energy carrier of the brain : present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (PubMed : 10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity). Required for mesendoderm differentiation (By similarity). See full target information SLC2A1

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