Anti-Glucose Transporter GLUT1 antibody [GLUT1/2476],Abcam,AB238051

Host

Mouse

Reactivity

Human

Application

IHC-P, PepArr

Platform ID

BAB944303512

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Glucose Transporter GLUT1 antibody [GLUT1/2476]
Cat. No.AB238051
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationIHC-P, PepArr
ClonalityMonoclonal
Clone NumberGLUT1/2476
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SLC2A1 aa 200-350. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed : 10227690, PubMed : 10954735, PubMed : 18245775, PubMed : 19449892, PubMed : 25982116, PubMed : 27078104, PubMed : 32860739). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed : 18245775, PubMed : 19449892). Most important energy carrier of the brain : present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (PubMed : 10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity). Required for mesendoderm differentiation (By similarity). See full target information SLC2A1

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