Anti-Gremlin 1 antibody,Abcam,AB231065
Host
Rabbit
Reactivity
Mouse
Application
WB
Platform ID
BAB011482515
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Gremlin 1 antibody
Cat. No.AB231065
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Chicken Gremlin-1 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop (PubMed : 12808456, PubMed : 15201225). Down-regulates the BMP4 signaling in a dose-dependent manner (PubMed : 15133038). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (By similarity). See full target information Grem1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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