Anti-HAX1 antibody,Abcam,AB137613

Host

Rabbit

Reactivity

Rat, Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB076862382

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-HAX1 antibody
Cat. No.AB137613
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration1.43 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human HAX1 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 10% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed : 26997484). Slows down the rate of inactivation of KCNC3 channels (PubMed : 26997484). Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. See full target information HAX1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.