Anti-HAX1 antibody [HL2170],Abcam,AB317151

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, IHC-P

Platform ID

BAB701874876

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-HAX1 antibody [HL2170]
Cat. No.AB317151
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberHL2170
ImmunogenRecombinant Fragment Protein within Human HAX1.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed : 26997484). Slows down the rate of inactivation of KCNC3 channels (PubMed : 26997484). Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. See full target information HAX1

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