Anti-HCN1 antibody [7C3],Abcam,AB252835

What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Rat

Reactivity

Mouse, Rat, Human

Application

WB, IHC-P

Platform ID

BAB327287178

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-HCN1 antibody [7C3]
Cat. No.AB252835
HostRat
IsotypeIgG1
ReactivityMouse, Rat, Human
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone Number7C3
Concentration0.899 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions (PubMed : 15351778, PubMed : 28086084). Displays lower selectivity for K(+) over Na(+) ions (PubMed : 28086084). Contributes to the native pacemaker currents in heart (If) and in the generation of the I(h) current which controls neuron excitability (PubMed : 29936235, PubMed : 30351409). Participates in cerebellar mechanisms of motor learning (By similarity). May mediate responses to sour stimuli (By similarity). See full target information HCN1

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