Anti-HCN1 antibody - C-terminal,Abcam,AB229340

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, IHC-P, IHC-Fr, ICC/IF

Platform ID

BAB952299672

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-HCN1 antibody - C-terminal
Cat. No.AB229340
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, IHC-P, IHC-Fr, ICC/IF
ClonalityPolyclonal
Concentration1.45 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human HCN1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions (PubMed : 15351778, PubMed : 28086084). Displays lower selectivity for K(+) over Na(+) ions (PubMed : 28086084). Contributes to the native pacemaker currents in heart (If) and in the generation of the I(h) current which controls neuron excitability (PubMed : 29936235, PubMed : 30351409). Participates in cerebellar mechanisms of motor learning (By similarity). May mediate responses to sour stimuli (By similarity). See full target information HCN1

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