Anti-HCN1 antibody [S70],Abcam,AB84816

The clone number has been updated from S70-28 to N70/28, both clone numbers name the same antibody clone.

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

IHC-Fr, IHC-P, Flow Cyt, WB

Platform ID

BAB264805919

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-HCN1 antibody [S70]
Cat. No.AB84816
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Human
ApplicationIHC-Fr, IHC-P, Flow Cyt, WB
ClonalityMonoclonal
Clone NumberS70
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Rat Hcn1 aa 750 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions (PubMed : 15351778, PubMed : 28086084). Displays lower selectivity for K(+) over Na(+) ions (PubMed : 28086084). Contributes to the native pacemaker currents in heart (If) and in the generation of the I(h) current which controls neuron excitability (PubMed : 29936235, PubMed : 30351409). Participates in cerebellar mechanisms of motor learning (By similarity). May mediate responses to sour stimuli (By similarity). See full target information HCN1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.