Anti-HCN2 antibody [S71],Abcam,AB84817

The clone number S71 has previously been called S71-37 and N71/37. These clone numbers all refer to the same antibody clone.

Host

Mouse

Reactivity

Mouse, Rat

Application

WB, IHC-Fr

Platform ID

BAB139843401

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-HCN2 antibody [S71]
Cat. No.AB84817
HostMouse
IsotypeIgG1
ReactivityMouse, Rat
ApplicationWB, IHC-Fr
ClonalityMonoclonal
Clone NumberS71
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Protein within Rat Hcn2 aa 750 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Hyperpolarization-activated ion channel that is permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions (PubMed : 10228147, PubMed : 22006928). Contributes to the native pacemaker currents in heart (If) and in neurons (Ih) (PubMed : 10228147, PubMed : 10524219). Can also transport ammonium in the distal nephron (By similarity). Involved in the initiation of neuropathic pain in sensory neurons (By similarity). See full target information HCN2

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