Anti-HCN4 antibody,Abcam,AB66501

Host

Rabbit

Reactivity

Human

Application

IHC-P

Platform ID

BAB702374636

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-HCN4 antibody
Cat. No.AB66501
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human HCN4. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLyophilized
ShippingBlue Ice
FormulationConstituents: Whole serum
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation (PubMed : 10228147, PubMed : 10430953, PubMed : 20829353). Exhibits higher selectivity for K(+) over Na(+) ions (PubMed : 10228147). Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable) (PubMed : 10228147, PubMed : 16407510, PubMed : 19165230). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli (By similarity). See full target information HCN4

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