Anti-HDAC10 antibody,Abcam,AB18971
This product is manufactured by BioVision, an Abcam company and was previously called 3610 HDAC10 Antibody. 3610-100 is the same size as the 100 µg size of ab18971.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB
Platform ID
BAB327587034
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed : 28516954). Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine (PubMed : 28516954). Histone deacetylase activity has been observed in vitro (PubMed : 11677242, PubMed : 11726666, PubMed : 11739383, PubMed : 11861901). Has also been shown to be involved in MSH2 deacetylation (PubMed : 26221039). The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak (PubMed : 28516954). May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells (PubMed : 23801752, PubMed : 29968769). May play a role in homologous recombination (PubMed : 21247901). May promote DNA mismatch repair (PubMed : 26221039). See full target information HDAC10
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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