Anti-HDAC4 antibody,Abcam,AB12172
What is this antibody validated in? Anti-HDAC4 antibody (ab12172) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of HDAC4? Anti-HDAC4 (ab12172) specifically detects a band for HDAC4 (UniProt: P56524) at a molecular weight of 119kDa. Trusted by the scientific community Anti-HDAC4 (ab12172) was first used in a scientific publication in 2004 and has been cited over 30 times in peer-reviewed journals. Reviewed by scientists Anti-HDAC4 (ab12172) has over 5 independent reviews from customers.
Host
Rabbit
Reactivity
Human, Rat, Mouse
Application
WB, IP, ICC/IF
Platform ID
BAB327786938
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1 (PubMed : 27708256). See full target information HDAC4
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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