Anti-HEXIM2 antibody,Abcam,AB127710

Host

Rabbit

Reactivity

Human

Application

ICC/IF, WB

Platform ID

BAB829736002

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-HEXIM2 antibody
Cat. No.AB127710
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB
ClonalityPolyclonal
Concentration0.81 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human HEXIM2 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed : 15713661, PubMed : 15713662). Core component of the 7SK RNP complex : in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed : 15713661, PubMed : 15713662). See full target information HEXIM2

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