Anti-HGF antibody [EGH2 4C12.1],Abcam,AB10829

Plasminogen related growth factors are potent effectors of growth, movement and differentiation of epithelia and endothelia. Membrane receptor for HGF/SF is the product of the proto-oncogene c-met a tyrosine kinase.

Host

Mouse

Reactivity

Human

Application

sELISA

Platform ID

BAB079960894

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-HGF antibody [EGH2 4C12.1]
Cat. No.AB10829
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationsELISA
ClonalityMonoclonal
Clone NumberEGH2 4C12.1
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human HGF. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed : 20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed : 15167892, PubMed : 20977675). Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed : 20977675). See full target information HGF

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