Anti-HNF-4-alpha antibody [EPR16885] - ChIP Grade,Abcam,AB181604

What is this antibody validated in? Anti-HNF-4-alpha antibody [EPR16885] - ChIP Grade (ab181604) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), ChIP in Human, Mouse, Rat samples. What is the molecular weight of HNF-4-alpha? Anti-HNF-4-alpha [EPR16885] - ChIP Grade (ab181604) specifically detects a band for HNF-4-alpha (UniProt: P49698) at a molecular weight of 53kDa. Trusted by the scientific community Anti-HNF-4-alpha [EPR16885] - ChIP Grade (ab181604) was first used in a scientific publication in 2015 and has been cited over 40 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR16885] also available for your convenience: ab181604, Carrier free - ab219610 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IP, ChIC/CUT&RUN-seq, WB, ChIP, IHC-P

Platform ID

BAB273201887

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-HNF-4-alpha antibody [EPR16885] - ChIP Grade
Cat. No.AB181604
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIP, ChIC/CUT&RUN-seq, WB, ChIP, IHC-P
ClonalityMonoclonal
Clone NumberEPR16885
Concentration1.34 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed : 30597922). Activates the transcription of CYP2C38 (By similarity). Represses the CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells (PubMed : 30530698). See full target information HNF4A

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