Anti-HNF1 alpha antibody,Abcam,AB96777

Host

Rabbit

Reactivity

Mouse, Human

Application

ICC/IF, IP, WB

Platform ID

BAB585808086

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-HNF1 alpha antibody
Cat. No.AB96777
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, IP, WB
ClonalityPolyclonal
Concentration1.27 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed : 10966642, PubMed : 12453420). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity).. (Microbial infection) Plays a crucial role for hepatitis B virus gene transcription and DNA replication. Mechanistically, synergistically cooperates with NR5A2 to up-regulate the activity of one of the critical cis-elements in the hepatitis B virus genome enhancer II (ENII). See full target information HNF1A

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