Anti-HSD17B4 antibody [2D3BB5BF10],Abcam,AB128565

This monoclonal antibody to HSD17B4 has been knockout validated in Western blot. The expected band was observed in wild type cells and the band was not seen in knockout cells. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Human

Application

ICC/IF, IP, WB

Platform ID

BAB218616836

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-HSD17B4 antibody [2D3BB5BF10]
Cat. No.AB128565
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationICC/IF, IP, WB
ClonalityMonoclonal
Clone Number2D3BB5BF10
Concentration1 mg/mL Batch dependent concentration
PurityPrecipitation Ammonium Sulphate
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: 99% HEPES buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway. Catalyzes two of the four reactions in fatty acid degradation : hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx. Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates. See full target information HSD17B4

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