Anti-Heme Oxygenase 1 antibody [EPR18161-128],Abcam,AB189491
What is this antibody validated in? Anti-Heme Oxygenase 1 antibody [EPR18161-128] (ab189491) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Heme Oxygenase 1? Anti-Heme Oxygenase 1 [EPR18161-128] (ab189491) specifically detects a band for Heme Oxygenase 1 (UniProt: P14901) at a molecular weight of 33kDa. Trusted by the scientific community Anti-Heme Oxygenase 1 [EPR18161-128] (ab189491) was first used in a scientific publication in 2017 and has been cited over 50 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Heme Oxygenase 1 antibody [EPR18161-128] (ab189491) has been confirmed by Western blot testing in HMOX1 Knockout A549 cell line, ab269503 . Other related products We have a range of other formats of antibody clone [EPR18161-128] also available for your convenience: ab189491, Carrier free - ab224677 , Alexa Fluor® 488 - ab237267 , Alexa Fluor® 647 - ab237268 , PE - ab237269 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, ICC/IF, Flow Cyt (Intra), IP, WB
Platform ID
BAB828536578
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Heme oxygenase 1. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron (PubMed : 11121422, PubMed : 19556236, PubMed : 7703255). Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis (PubMed : 20055707).. Heme oxygenase 1. (Microbial infection) During SARS-COV-2 infection, promotes SARS-CoV-2 ORF3A-mediated autophagy but is unlikely to be required for ORF3A-mediated induction of reticulophagy.. Heme oxygenase 1 soluble form. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. See full target information HMOX1
Category Paths
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