Anti-Heme Oxygenase 1 antibody [HO-1-1],Abcam,AB13248

What is this antibody validated in? Anti-Heme Oxygenase 1 antibody [HO-1-1] (ab13248) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), ELISA in Cow, Dog, Human, Mouse, Rat samples. What is the molecular weight of Heme Oxygenase 1? Anti-Heme Oxygenase 1 [HO-1-1] (ab13248) specifically detects a band for Heme Oxygenase 1 (UniProt: P09601) at a molecular weight of 34.6kDa. Trusted by the scientific community Anti-Heme Oxygenase 1 [HO-1-1] (ab13248) was first used in a scientific publication in 2004 and has been cited over 320 times in peer-reviewed journals. Reviewed by scientists Anti-Heme Oxygenase 1 [HO-1-1] (ab13248) has over 15 independent reviews from customers.

Host

Mouse

Reactivity

Mouse, Rat, Cow, Dog, Human

Application

IHC-P, sELISA, WB, Flow Cyt (Intra)

Platform ID

BAB703574060

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Heme Oxygenase 1 antibody [HO-1-1]
Cat. No.AB13248
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Cow, Dog, Human
ApplicationIHC-P, sELISA, WB, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberHO-1-1
ImmunogenSynthetic Peptide within Human HMOX1 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Heme oxygenase 1. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron (PubMed : 11121422, PubMed : 19556236, PubMed : 7703255). Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis (PubMed : 20055707).. Heme oxygenase 1. (Microbial infection) During SARS-COV-2 infection, promotes SARS-CoV-2 ORF3A-mediated autophagy but is unlikely to be required for ORF3A-mediated induction of reticulophagy.. Heme oxygenase 1 soluble form. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. See full target information HMOX1

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