Anti-Hepcidin-25 antibody,Abcam,AB30760
What is this antibody validated in? Anti-Hepcidin-25 antibody (ab30760) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Rat samples. What is the molecular weight of Hepcidin-25? Anti-Hepcidin-25 (ab30760) specifically detects a band for Hepcidin-25 (UniProt: P81172) at a molecular weight of 3kDa. Trusted by the scientific community Anti-Hepcidin-25 (ab30760) was first used in a scientific publication in 2007 and has been cited over 40 times in peer-reviewed journals. Reviewed by scientists Anti-Hepcidin-25 (ab30760) has over 5 independent reviews from customers.
Host
Rabbit
Reactivity
Rat, Human
Application
IHC-P, WB
Platform ID
BAB954398664
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma (PubMed : 22682227, PubMed : 29237594, PubMed : 32814342). Controls the major flows of iron into plasma : absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed : 22306005).. Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa (PubMed : 11034317, PubMed : 11113131). See full target information HAMP
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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