Anti-Hexokinase II antibody,Abcam,AB227198

Host

Rabbit

Reactivity

Rat, Human, Mouse

Application

ICC/IF, WB, IHC-P

Platform ID

BAB267304719

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Hexokinase II antibody
Cat. No.AB227198
HostRabbit
IsotypeIgG
ReactivityRat, Human, Mouse
ApplicationICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration0.63 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human HK2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed : 23185017, PubMed : 26985301, PubMed : 29298880). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed : 29298880). Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis (PubMed : 18350175). See full target information HK2

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